Acute Q fever and the risk of developing endocarditis

Autor: A, Martín-Aspas, C, Collado-Pérez, L, Vela-Manzano, C, Fernández-Gutiérrez Del Álamo, I, Tinoco-Racero, J A, Girón-González
Rok vydání: 2014
Zdroj: Revista clinica espanola. 215(5)
ISSN: 2254-8874
Popis: Assess clinical and serological data as parameters indicative of a possible evolution to endocarditis after an episode of acute Q fever.Retrospective cohort study of evolution to endocarditis after an acute Q fever episode, analyzing the clinical and serological evolution and the antibiotic treatment administered.Eighty patients were recruited, 20% of whom had phase i IgG antibody levels ≥ 1:1024 in the first 3 months. Only 44% of the patients underwent antibiotherapy in the acute phase; only 2 patients underwent extended antibiotherapy. Fifteen percent of the patients underwent an echocardiogram. None of the patients had symptoms suggestive of chronic infection or progressed to endocarditis after a median follow-up of 100 months, regardless of the early increase in phase i IgG antibodies.The early increase in phase i IgG antibodies in asymptomatic patients is not associated with progression to endocarditis despite not undergoing prolonged antibiotic treatment.
Databáze: OpenAIRE