| Autor: |
Sandra L, Rebholz, John T, Melchior, Jeffrey A, Welge, Alan T, Remaley, W Sean, Davidson, Laura A, Woollett |
| Rok vydání: |
2017 |
| Předmět: |
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| Zdroj: |
Journal of clinical and laboratory medicine |
| ISSN: |
2572-9578 |
| Popis: |
World-wide, millions of women enter preterm labor or have small newborns. Effective biomarkers are needed to identify women at risk for these adverse outcomes. A time and cost effective way to examine any potentially new biomarkers in samples collected during prior studies or trials that had been assayed for other metabolites would be highly useful. Thus, the current study aimed to determine if samples that had been previously thawed and re-frozen could be re-assayed for novel biomarkers, those being lipoprotein composition (sizing, proteome, lipids) and combined cholesterol and cytokine concentrations. Fasting blood was collected from 51 young non-pregnant women and plasma was analyzed for lipoprotein composition and cytokine concentrations after multiple freeze/thaw cycles in the cold or at room temperature and after being stored for 18 months. Plasma LDL-C, HDL-C, total cholesterol, and triglyceride concentrations decreased |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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