[Physico-chemical properties of borate derivatives of DOPA, dopamine, and their liposome forms]

Autor: N V, Borisova, V I, Kriukov, A P, Kaplun, V I, Shvets
Rok vydání: 1999
Předmět:
Zdroj: Bioorganicheskaia khimiia. 24(11)
ISSN: 0132-3423
Popis: To increase the solubility of L-3,4-dihydroxyphenylalanine (DOPA) and dopamine (DA) incorporated in liposomes, it was suggested to convert them into ammonium and 1-adamantylammonium borate complexes. The structure of these complexes was studied by 11B and 1H NMR, IR, and mass spectrometry and conductometry. The liposomic form of the complexes is characterized by a high active compound/lipid molar ratio (0.5). Catechols in the form of complex salts are retained better within the inner volume of liposomes.
Databáze: OpenAIRE