| Autor: |
Sylwia, Kwiatkowska, Maria, Luczyńska, Iwona, Grzelewska-Rzymowska, Dariusz, Nowak, Marek, Zieba |
| Rok vydání: |
2005 |
| Předmět: |
|
| Zdroj: |
Polski merkuriusz lekarski : organ Polskiego Towarzystwa Lekarskiego. 19(109) |
| ISSN: |
1426-9686 |
| Popis: |
Tuberculosis and sarcoidosis represent the granulomatous diseases. The aim of the study was to compare the markers of oxidative stress: in exhaled breath condensate (EBC) and in serum of patients with tuberculosis and sarcoidosis.19 patients with active lung tuberculosis and 15 patients with sarcoidosis were enrolled into the study. As a control served 15 healthy subjects. Hydrogen peroxide (H2O2) was measured in EBC and the ends products of lipid peroxidation (TBARs) were assessed in serum.The concentrations of H202 and TBARs (1022.96+/-186.02 nM and 4.22+/-0. 80 microM, respectively) were significantly higher in patients with tuberculosis as compared with the controls (398.15+/-37.10 nM and 0.48+/-0.17 microM, respectively). The patients with sarcoidosis revealed only the significantly elevated levels of hydrogen peroxide (963.30+/-105.77 nM) in breath condensate.It was found that local and systemic oxidative stress were present in patients with tuberculosis, while in those with sarcoidosis existed only the local reaction. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
|
