| Autor: |
S V, Iakovlev, L I, Dvoretskiĭ, T V, Shakhova |
| Rok vydání: |
2000 |
| Předmět: |
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| Zdroj: |
Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic]. 45(3) |
| ISSN: |
0235-2990 |
| Popis: |
Efficacy of ticarcillin/clavulanate was studied in the treatment of 11 patients with severe community- and hospital-acquired pneumonia in an open controlled trial. The drug was administered in a dose of 3.1 g every 4 or 6 hours depending on the infection severity. When pneumonia was due to Pseudomonas aeruginosa, amikacin was additionally used. The positive clinical effect of ticarcillin/clavulanate was stated in 73 per cent of the patients. The pathogen eradication was stated in all the patients. However, in 2 cases superinfection due to P.aeruginosa developed. Mild adverse effects were observed in 2 cases. It is concluded that ticarcillin/clavulanate is highly efficient in the treatment of patients with severe or complicated pneumonia. In cases with ventilator-associated pneumonia it is advisable to use ticarcillin/clavulanate in combination with an aminoglycoside. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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