[Multicenter study of sodium alginate in the treatment of regurgitation in infants]

Autor: B, Le Luyer, J F, Mougenot, L, Mashako, P, Chapoy, J P, Olives, A, Morali, B, Chevallier, J L, Ginies, C, Dupont, M, Dagorne
Jazyk: francouzština
Rok vydání: 1992
Předmět:
Zdroj: Annales de pediatrie. 39(10)
ISSN: 0066-2097
Popis: An open multicenter study was performed to assess the efficacy and safety of alginic acid in two different dosages in 76 pediatric patients with gastroesophageal reflux confirmed by pH monitoring. Among the 69 patients in whom endoscopy was carried out before treatment, 18 had erythematous esophagitis and 5 had erosive esophagitis. Irrespective of the dosage used, the frequency of regurgitation and vomiting decreased significantly (p0.00001 and p = 0.01, respectively). Clinical and biochemical tolerance were outstanding and no adverse effects were recorded. On the basis of these data, the recommended dosage is 1 to 2 ml/kg/day in divided doses after meals.
Databáze: OpenAIRE