| Autor: |
S K, Nolting, A, Gupta, P D, Doncker, M L, Jacko, B L, Moskovitz |
| Rok vydání: |
1999 |
| Předmět: |
|
| Zdroj: |
European journal of dermatology : EJD. 9(7) |
| ISSN: |
1167-1122 |
| Popis: |
Over the past 10 years, itraconazole has been used to treat more than 34 million patients worldwide. We present a review of the safety of various continuous itraconazole schedules used in the treatment of dermatomycosis and onychomycosis. Data from controlled clinical trials and extensive post-marketing surveillance show that itraconazole has an impressive safety profile at a dose of 50-200 mg/day for 1-4 weeks for dermatomycosis and 200 mg/day for 3 months for onychomycosis. In addition, itraconazole is safe to use in diabetic patients with dermatomycosis or onychomycosis. Short-term, intermittent itraconazole regimens, which may offer additional benefits in terms of safety and cost, have now been introduced. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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