The control of impurities in amitriptyline hydrochloride using a reversed-phase hybrid stationary phase

Autor:	S P, Dixon, A, Lodi, J H M, Miller, G G, Skellern
Rok vydání:	2007
Předmět:	Time Factors Drug Stability Molecular Structure Viscosity Amitriptyline Temperature Reproducibility of Results Dibenzocycloheptenes Antidepressive Agents Tricyclic Drug Contamination Mass Spectrometry Chromatography Liquid
Zdroj:	Pharmeuropa scientific notes. 2005(1)
ISSN:	1814-2435
Popis:	An isocratic reversed-phase liquid chromatographic method is described using a hybrid column for the control of synthetic impurities potentially found in amitriptyline hydrochloride. The method has been validated and is capable of controlling impurities to 0.1 per cent.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=pmid________::aed47bdc15da4394936a1892b23fc07e https://pubmed.ncbi.nlm.nih.gov/17687889 Zobrazit plný text záznamu