| Autor: |
N, Mucci, A, Ianni, C L, Ursini, D, Arzani, N K, Bhat, P, Navarra, V, Romano-Spica |
| Rok vydání: |
2002 |
| Předmět: |
|
| Zdroj: |
In vivo (Athens, Greece). 15(6) |
| ISSN: |
0258-851X |
| Popis: |
We have previously shown that electromagnetic field (EMF) exposure induces ETS1 oncogene overexpression in different cell lines. In order to investigate in vivo EMF effects, BALB/c mice were exposed at different times to 50 MHz radiation, modulated (80%) at 16 Hz. The exposed and control animals were sacrificed and the spleen excised for rt-pcr and western blot analysis. We observed an increase in ETS1 mRNA and protein expression, but a decrease in ETS2 protein levels. Preliminary results from this experimental model show in vivo evidence of the effect of EMF on ETS oncogene expression. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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