| Autor: |
Dong-Sung, Lee, Sun Hee, Cheong |
| Rok vydání: |
2017 |
| Předmět: |
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| Zdroj: |
Advances in experimental medicine and biology. |
| ISSN: |
0065-2598 |
| Popis: |
Glutamate-induced oxidative neurotoxicity plays a part role in neuronal degeneration on the disorders of central nervous system (CNS). The expression of heme oxygenase (HO)-1 mediated by Inducible nuclear factor-E2-related factor 2 (Nrf2) functions as an anti-oxidants that is able to play an important role in the pathogenesis of several neuronal disorders. In the present study, taurine showed the inhibitory effect against reactive oxygen species (ROS) induction and protective effects against neurotoxicity induced by glutamate- and H |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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