Synthetic Studies on FNC-RED and Its Analogues Containing an All

Autor: Shinsuke, Inuki, Keisuke, Sato, Naoto, Zui, Ryosuke, Yamaguchi, Takanori, Matsumaru, Yukari, Fujimoto
Rok vydání: 2019
Předmět:
Zdroj: The Journal of organic chemistry. 84(19)
ISSN: 1520-6904
Popis: FNC-RED exhibits innate immune receptor Toll-like receptor 4 (TLR4)/myeloid differentiation factor-2 (MD2) stimulatory activity. We have developed a divergent synthetic route to FNC-RED derivatives containing various alkyl side chains. Key features of the synthetic study include stepwise palladium catalyzed cross-coupling reactions and the construction of an all
Databáze: OpenAIRE