| Autor: |
Leah I, Elizondo, Eric L, Vu, Kathleen K, Kibler, Danielle R, Rios, R Blaine, Easley, Dean, Andropoulos, Sebastian, Acosta, Craig, Rusin, Kenneth, Brady, Christopher J, Rhee |
| Rok vydání: |
2021 |
| Předmět: |
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| Zdroj: |
Acta neurochirurgica. Supplement. 131 |
| ISSN: |
0065-1419 |
| Popis: |
The critical closing pressure (CrCP) of the cerebral vasculature is the arterial blood pressure (ABP) at which cerebral blood flow (CBF) ceases. Because the ABP of preterm infants is low and close to the CrCP, there is often no CBF during diastole. Thus, estimation of CrCP may become clinically relevant in preterm neonates. Transcranial Doppler (TCD) ultrasound has been used to estimate CrCP in preterm infants. Diffuse correlation spectroscopy (DCS) is a continuous, noninvasive optical technique that measures microvascular CBF. Our objective was to compare and validate CrCP measured by DCS versus TCD ultrasound. Hemorrhagic shock was induced in 13 neonatal piglets, and CBF was measured continuously by both modalities. CrCP was calculated using a model of cerebrovascular impedance, and CrCP determined by the two modalities showed good correlation by linear regression, median r |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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