| Autor: |
Victor, Monteon, Ivan, May-Gil, Karla, Acosta-Viana, Angel, Ramos-Logonio, Oscar, Hernandez, Ruth, Lopez |
| Rok vydání: |
2017 |
| Předmět: |
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| Zdroj: |
Annals of parasitology. 63(2) |
| ISSN: |
2299-0631 |
| Popis: |
An immune response to triatomine’s saliva is an immunological marker of exposure to triatomine bites. However, considerable variability in salivary protein profiles did exist among species. In the present work, we compare salivary proteins from Mexican Triatoma dimidiata and Rhodnius prolixus using 2-D electrophoresis. A clear differential saliva profile was found to exist between these two triatomine species. Fewer protein spots were detected in R. prolixus than in T. dimidiata. More than half of the proteins had an isoelectric point between 5 and 7 and a molecular weight between 10 and 30 kDa in T. dimidiata. Mice exposed to T. dimidiata saliva mount an immune response to three major cross-reacting antigens in R. prolixius saliva with weights of 10 kDa and 55 kDa. Our findings may alert for the presence of cross-reacting antigens between triatomine species in regions where two or more species are overlapping in the same geographical area. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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