Autor: |
Bjornstad, Petter, Maahs, David M., Roncal, Carlos A., Snell-Bergeon, Janet K., Shah, Viral N., Harra, Tamara, Ellis, Samuel L., Hatch, Matthew, Chung, Linh T., Rewers, Marian J., Garg, Satish, Cherney, David Z., Pyle, Laura, Nadeau, Kristen J., Johnson, Richard J. |
Jazyk: |
angličtina |
Rok vydání: |
2018 |
Předmět: |
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Popis: |
Uricosuria and crystallization are increasingly recognized risk factors for diabetic tubulopathy. This pilot clinical trial aimed to determine the acute effect of urinary alkalinization using oral sodium bicarbonate [NaHCO(3)] on UA crystals in adults with type 1 diabetes (T1D). Adults with T1D ages 18–65 years (n=45, 60% female, HbA1c 7.5±1.2%, 20.2±9.3 years duration) without chronic kidney disease (eGFR ≥60ml/min/1.73m(2) and albumin-to-creatinine ratio |
Databáze: |
OpenAIRE |
Externí odkaz: |
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