Treatment of advanced localised prostatic cancer by orchiectomy, radiotherapy, or combined treatment. A Medical Research Council Study. Urological Cancer Working Party--Subgroup on Prostatic Cancer

Autor:	G J, Fellows, P B, Clark, L L, Beynon, J, Boreham, C, Keen, M C, Parkinson, R, Peto, J N, Webb
Rok vydání:	1992
Předmět:	Male Radiotherapy Risk Factors Prostate Humans Prostatic Neoplasms Combined Modality Therapy Orchiectomy
Zdroj:	British journal of urology. 70(3)
ISSN:	0007-1331
Popis:	A total of 277 patients with apparently localised prostatic cancer (T2-T4 NXMO) were allocated at random to receive radiotherapy alone (88), orchiectomy alone (90) and combined therapy (99) between 1980 and 1985. The main outcome measures were survival, time to appearance of metastases and treatment of local disease progression by further transurethral resection. Orchiectomy, whether alone or with radiotherapy, produced a significant delay in detection of metastases when compared with radiotherapy alone. There were no statistically significant differences between the 3 treatment groups in local disease control or in overall survival.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=pmid________::ad24d24030ec0956e6e16c5f5f3ff187 https://pubmed.ncbi.nlm.nih.gov/10071576 Zobrazit plný text záznamu Plný text