Chromosomal changes in a dedifferentiated chondrosarcoma: a case report and review of the literature

Autor:	D P, O'Malley, K E, Opheim, T S, Barry, D B, Chapman, M J, Emond, E U, Conrad, T H, Norwood
Rok vydání:	2001
Předmět:	Chromosome Aberrations Femoral Neoplasms Chondrosarcoma Humans Female Middle Aged Arthroplasty Replacement Knee Chromosomes Human Pair 19
Zdroj:	Cancer genetics and cytogenetics. 124(2)
ISSN:	0165-4608
Popis:	The chromosome abnormalities observed in a dedifferentiated chondrosarcoma are reported. A new molecular cytogenetic technique, spectral karyotyping, was used to identify and confirm structural rearrangements in this case. A review of the literature revealed that nine cases have been reported, in eight of which a complete description of the cytogenetic abnormalities was described. Structural aberrations were most frequently reported in chromosomes 1 and 9, and chromosomes 7 and 19 were most frequently observed to be involved in numerical aberrations (trisomy and tetrasomy). In chondrosarcomas, structural aberrations in chromosomes 1 and 9 and trisomy or tetrasomy of chromosome 7 are among the more frequently observed aberrations.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=pmid________::ad1b2929a3bfec68a5cc548fc3bbf201 https://pubmed.ncbi.nlm.nih.gov/11172900 Zobrazit plný text záznamu Full Text from ScienceDirect