Safety evaluation of Bon-santé cleanser
| Autor: | O, Awodele, O E, Kale, A O, Odewabi, M, Ekor, B A, Salau, A O, Adefule-Ositelu |
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| Rok vydání: | 2017 |
| Předmět: | |
| Zdroj: | Journal of Traditional and Complementary Medicine |
| ISSN: | 2225-4110 |
| Popis: | Background The global increase in acceptance and use of herbal remedies in recent times is still accompanied with poor knowledge of their potential adverse effects and the toxicological implications of their use are underestimated. Methods Bon-santé Cleanser® (BSC), a polyherbal containing Anogeissus leiocarpus, Terminalia ivorensis, Massularia acuminate and Macuna pruriens, is an “energizer and hormone booster”. We assessed the effect of BSC on reproductive function after administration for 60 days in male Wistar rats. Rats (150–300 g) were assigned into four groups of 8/group. Control received distilled water (10 ml/kg) while other groups received BSC 250, 500 and 1000 mg/kg/day p.o. respectively. Animals were euthanized by cervical dislocation and samples collected for analysis. Results BSC (250 mg/kg) elevated (p Graphical abstract Safety evaluation of Bon-santé cleanser® polyherbal in male Wistar rats: Further investigations on androgenic and toxicological profile.Image 1 |
| Databáze: | OpenAIRE |
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