| Autor: |
A, Hafi, J L, Cluet, N, Pages, G, Fournier, R, Alcindor, C, Boudene |
| Rok vydání: |
1991 |
| Předmět: |
|
| Zdroj: |
Research communications in chemical pathology and pharmacology. 71(1) |
| ISSN: |
0034-5164 |
| Popis: |
We have studied the effect of a chronic pretreatment by lead on the peroxidation processes by measuring the production of the four main volatile hydrocarbons: ethane and pentane as index of lipid peroxidation; propane as marker of protein peroxidation and ethylene as index of both lipid and protein peroxidations. Our results have shown that: 1) lead alone did not increase the physiological formation of alkanes indicating that lead is not able per se to initiate the peroxidative processes; 2) after phenylhydrazine injection, lipid peroxidation makers were not modified, except pentane in male lead-treated rats. Conversely, ethylene and propane exhalation were increased 45 min after phenylhydrazine injection in lead-treated rats indicating a potentialisation of the oxidative effect of phenylhydrazine, mainly on proteins, by lead. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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