[A model of cooperative rearrangements of biological membranes without changes in the affinity of receptor binding centers]
| Autor: | G V, Kaler |
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| Rok vydání: | 1985 |
| Předmět: | |
| Zdroj: | Biofizika. 30(3) |
| ISSN: | 0006-3029 |
| Popis: | A mathematical model is proposed for cooperative rearrangements induced by specific ligand in certain biomembrane domains. They are considered as the N-valent receptors undergoing rearrangement when n less than or equal to N ligand-binding receptor sites are occupied. The model predicts distinct sigmoidal dependence for change of some structural parameter on ligand concentration when the receptor site-ligand affinity remains constant as binding rises (positive cooperativity is absent). |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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