cGAS-STING-mediated DNA sensing maintains CD8

Autor: Wenwen, Li, Lu, Lu, Juanjuan, Lu, Xinran, Wang, Chao, Yang, Jingsi, Jin, Lingling, Wu, Xiaochuan, Hong, Fanlin, Li, Dongqing, Cao, Yuanqin, Yang, Meng, Wu, Bing, Su, Jinke, Cheng, Xuanming, Yang, Wen, Di, Liufu, Deng
Rok vydání: 2019
Předmět:
Zdroj: Science translational medicine. 12(549)
ISSN: 1946-6242
Popis: Although cGAS-STING-mediated DNA sensing in tumor cells or phagocytes is central for launching antitumor immunity, the role of intrinsic cGAS-STING activation in T cells remains unknown. Here, we observed that peripheral blood CD8
Databáze: OpenAIRE