The Link Between Bone Osteocalcin and Energy Metabolism in a Group of Postmenopausal Women
| Autor: | DUMITRU, N, CARSOTE, M, COCOLOS, A, PETROVA, E, OLARU, M, DUMITRACHE, C, GHEMIGIAN, A |
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| Jazyk: | angličtina |
| Rok vydání: | 2019 |
| Předmět: | |
| Zdroj: | Current Health Sciences Journal |
| ISSN: | 2069-4032 2067-0656 |
| Popis: | There is a dual relationship between bone and tissues involved in energy metabolism (fat tissue and beta-pancreatic cells). Thus, bone remodeling is an energy consuming process, but osteocalcin, the main on-collagenic protein, synthesized by osteoblas during bone formation exerts a number of biological effects on beta-pancreatic and adipose cells. With this data, we wanted to see if the presence of a chronic metabolic disorder such as type 2 diabetes mellitus (T2DM) influence this complex dual relationship. For this, we conducted a cross-sectional study to evaluate the relation between osteocalcin and energetic metabolism in a group of 146 postmenopausal womens with and without T2DM at CI Parhon National Institute of Endocrinology, Bucharest. Clinical, metabolic and hormonal parameters were evaluated. For statistical analysis we used Student t-test and the Spearman correlation (statistical significance: p |
| Databáze: | OpenAIRE |
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