[Clinical studies of cefotaxime in infections in internal medicine]

Autor: H, Kawasaki, T, Suou, K, Watanabe, K, Yoshida, H, Sasaki, Y, Kishimoto, T, Sugihara, S, Ishitobi, S, Kanno, I, Tsuruhara
Rok vydání: 1984
Předmět:
Zdroj: The Japanese journal of antibiotics. 37(9)
ISSN: 0368-2781
Popis: Clinical studies on a new cephalosporin antibiotic, cefotaxime (CTX) were carried out in 79 patients with various types of infections in internal medicine. The efficacy rates were 65.8% in 39 cases of respiratory tract infections, 94.1% in 17 cases of biliary tract infections, 75.0% in 12 cases of urinary tract infections, 80.0% in 11 cases of other infections, and 75.3% in all cases. After CTX therapy, body temperature was improved in 76.7% of all 79 patients, particularly being excellent in all cases of biliary tract infections. Furthermore, symptoms such as cough, dyspnea, chest pain, moist rale and anorexia were improved to a great degree after CTX therapy. Adverse reactions and abnormal laboratory findings consisted of mild liver injury in 1 out of 79 cases. CTX was assessed to be an effective antibiotic for various types of infections in internal medicine.
Databáze: OpenAIRE