Risk of Hospitalization in Under-five Children With Community-Acquired Pneumonia: A Multicentric Prospective Cohort Study

Autor: Javeed Iqbal, Bhat, Bashir A, Charoo, Aparna, Mukherjee, Ridwana, Ahad, Rashmi R, Das, Jagdish Prasad, Goyal, Bhadresh, Vyas, Vinod H, Ratageri, Rakesh, Lodha, S K, Kabra
Rok vydání: 2021
Předmět:
Zdroj: Indian pediatrics. 58(11)
ISSN: 0974-7559
Popis: To evaluate factors associated with risk of hospitalization in children with community-acquired pneumonia (CAP).Prospective cohort study.Multi-site hospital based study.A separate acute respiratory tract infection (ARI) treatment unit (ATU) was established. The revised WHO case definition for ARI was used across all the study sites to ensure uniformity in management of ARI patients (2-59 months). Clinical history, examination findings and investigations of enrolled patients were recorded on a predesigned case record form. Children were followed up at 1 week (± 1 day).Risk factors for hospitalization among pneumonia patients.A total of 7026 children with the diagnosis of ARI were enrolled. Pneumonia was diagnosed in 938 (13.4%) patients (median (IQR) age: 15 (8, 25) months; 63.5% boys). Hospitalization was needed in 56.8% of pneumonia patients. On multi-variate analysis, factors associated with risk of hospitalization were: Oxygen saturation on pulse oximetry (SpO2)92% in room air (OR 7.04; 95% CI 1.6, 30.8, P=0.01), procalcitonin level0.5 ng/mL (OR: 7.5, 95% CI: 1.0, 57.7, P=0.05), and lower weight for height z-score (OR 0.8; 95% CI: 0.6, 0.9, P=0.02).Present study found SpO292% at room air, serum procalcitonin level0.5 ng/mL and lower weight for height z-score to be predictors for risk of hospitalization in under-five children presenting with community acquired pneumonia. These factors can be utilized to assess a child with CAP regarding the need of hospitalization.
Databáze: OpenAIRE