[Continuous cell subline A4C2/9K and its application to the african swine fever virus study]

Autor: V I, Balysheva, E Yu, Prudnikova, T V, Galnbek, V M, Balyshev
Rok vydání: 2015
Předmět:
Zdroj: Voprosy virusologii. 60(2)
ISSN: 0507-4088
Popis: A new continuous cell subline A4C2/9K highly sensitive to the african swine fever virus (ASFV) was prepared. All the tested ASFV strains isolated in the Russian Federation in 2008-2013 proliferated in this cell culture exhibiting hemadsorption and accumulated at a titer of up to 6.5 Ig HAU50/cm3. The cell culture A4C2/9K can be used for ASFV isolation or determination of its infectious activity and serotype identity. The culture versions of the ASFV strain Stavropol 01/08 at passages 24 and 33 in the cell culture A4C2/9K lost their pathogenicity for pigs.
Databáze: OpenAIRE