[Therapeutic use of intravenous immunoglobulins in the antiphospholipid syndrome]

Autor: J C, Piette, D, Lê Thi Huong, B, Wechsler
Jazyk: francouzština
Rok vydání: 2000
Předmět:
Zdroj: Annales de medecine interne. 151
ISSN: 0003-410X
Popis: Although experience remains limited and uncontrolled, intravenous immunoglobulin (IVIg) therapy probably has a place in the management of selected patients with the antiphospholipid syndrome. It seems effective for the prevention of recurrent pregnancy losses when conventional strategies using subcutaneous heparin and low-dose aspirin have failed. IVIg are currently investigated in the treatment of recurrent in vitro fertilization failure associated with antiphospholipid antibodies. In patients with severe thrombocytopenia, IVIg usually induce a prompt but transient remission. Finally, IVIg associated with steroids and heparin might improve survival in the rare but life-threatening catastrophic antiphospholipid syndrome.
Databáze: OpenAIRE