[Current approaches to surgical treatment of liver tumors]
| Autor: | Iu I, Patiutko, I V, Sagaĭdak, A G, Kotel'nikov, Kh V, Badalian, A O, Tumanian |
|---|---|
| Rok vydání: | 1999 |
| Předmět: |
Male
Postoperative Care Reoperation Antimetabolites Antineoplastic Laser Coagulation Time Factors Ultrasonic Therapy Liver Neoplasms Leucovorin Interferon-alpha Antineoplastic Agents Interferon alpha-2 Prognosis Combined Modality Therapy Hemostasis Surgical Recombinant Proteins Postoperative Complications Adjuvants Immunologic Chemotherapy Adjuvant Interferon Type I Hepatectomy Humans Female Fluorouracil Liver Failure |
| Zdroj: | Voprosy onkologii. 44(5) |
| ISSN: | 0507-3758 |
| Popis: | Since 1990, 230 operations for focal pathologies in the liver have been carried out at the Center's clinics using such advanced procedures and equipment as radio-isotope examination of hepatic function, ultrasonography of the liver during surgery, ultrasound aspirator, water-flow scalpel, argon coagulator and adhesive dressing materials. The study included 75 resections for primary hepatic tumor (lethality-14.6%), 114 resections-disseminated tumor (lethality-5.2%) and 41 resections for benign tumors and non-tumor pathologies (no lethality). Preoperative chemotherapy was found to significantly increase the risk of postoperative complications in cases of liver resection. Five-year survival in such patients with primary tumor was 33.3%. The seven most significant prognostic factors in primary hepatic carcinoma were: portal invasion by tumor cells, number of tumor nodes in the liver, alpha-fetoprotein concentration, tumor node size, concomitant cirrhosis, age and extent of surgery. In patients with hepatic resection for solitary metastasis of the large bowel, 5-year survival was 28.6%. A regimen of adjuvant chemotherapy for solitary metastasis of colorectal cancer into liver is suggested. The data on 37 surgical patients with hepatic metastasis of non-colorectal cancer are presented. It was demonstrated that the liver should be resected in cases of solitary metastasis of renal carcinoma, adrenal gland, ovary, tests, breast, gallbladder and carcinoid. |
| Databáze: | OpenAIRE |
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