Melatonin decreases circulating

Autor: Maiara Voltarelli, Providello, Gisele Bulhões, Portapilla, Pedro Alexandre Sampaio, Oliveira, Carla Brigagão Pacheco, da Silva, Naira Ferreira, Anchieta, Carlos Renato, Tirapelli, Sérgio, de Albuquerque
Rok vydání: 2020
Předmět:
Zdroj: Canadian journal of physiology and pharmacology. 99(8)
ISSN: 1205-7541
Popis: Cardiac damage during the acute phase of Chagas disease (CD) is associated with an increase in pro-inflammatory markers and oxidative stress. Melatonin (MEL) has emerged as a promising therapy for CD due to its antioxidant and immunomodulatory properties; however, the protective action of MEL in the cardiac tissue, as well as its direct action on the parasite cycle, is not fully understood. We investigated the effects of MEL on heart parasitism in mice infected with
Databáze: OpenAIRE