Ca

Autor:	Seisuke, Noguchi, Yusuke, Kondo, Rina, Ito, Takahiro, Katayama, Shunsuke, Kazama, Yoshihiro, Kadota, Yasuyuki, Kitaura, Robert A, Harris, Yoshiharu, Shimomura
Rok vydání:	2018
Předmět:	Male Rats Sprague-Dawley Serine Animals Calcium Phosphorylation Thiamine Pyrophosphate Muscle Skeletal Protein Kinase Inhibitors Protein Kinases 3-Methyl-2-Oxobutanoate Dehydrogenase (Lipoamide) Mitochondria Muscle
Zdroj:	Biochemical and biophysical research communications. 504(4)
ISSN:	1090-2104
Popis:	Catabolism of the branched-chain amino acids (BCAAs: leucine, isoleucine, and valine) is regulated by the branched-chain α-ketoacid dehydrogenase (BCKDH) complex, which in turn is regulated by phosphorylation catalyzed by BCKDH kinase (BDK). Thiamine pyrophosphate (TPP) is required as a coenzyme for the E1 component of the BCKDH complex and can also bring about activation of the complex by inhibiting BDK. The present study shows that free Ca
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=pmid________::aab760f789f7351c88aa71ffcb6d9748 https://pubmed.ncbi.nlm.nih.gov/30224059 Zobrazit plný text záznamu Full Text from ScienceDirect