Seroprevalence of acquired toxoplasmosis in HIV-infected and apparently healthy individuals in Jos, Nigeria
| Autor: | C J, Uneke, D D, Duhlinska, M O, Njoku, B A F, Ngwu |
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| Rok vydání: | 2005 |
| Předmět: |
Adult
Male Meat Adolescent Antibodies Protozoan Nigeria Enzyme-Linked Immunosorbent Assay Food Contamination HIV Infections Rodentia Comorbidity Cat Diseases Sampling Studies Rodent Diseases Soil Food Parasitology HIV Seroprevalence Seroepidemiologic Studies Zoonoses Animals Humans Child Aged Middle Aged Agricultural Workers' Diseases Toxoplasmosis Animal Immunoglobulin G Cats Female Toxoplasma Toxoplasmosis |
| Zdroj: | Parassitologia. 47(2) |
| ISSN: | 0048-2951 |
| Popis: | Toxoplasma gondii IgG antibody seroprevalence was studied in two different populations of 219 HIV-infected patients and 144 apparently healthy individuals (AHIs). Clinical toxoplasmosis was assessed among the HIV-infected patients. Antibodies to T. gondii were detected in 85 (38.8%, 95% CI: 32.36%-45.26%) of the HIV-infected patients and in 30 (20.8%, 95% CI: 14.20%-27.46%) of the AHIs. Among the AIHs, males represented 22.0% of infections compared to females (20.0%) and individuals within age group 21-30 years accounted for the highest prevalence of 33.3% (95% CI: 11.56%-55.10%). There was no significant difference in the trend (Chi-square, Por = 0.05). Assessment of epidemiological factors showed higher seroprevalence of Toxoplasma antibodies among those who eat rodents (29.6%) and those who constantly have contact with the soil (21.2%). Among the HIV-infected, individuals 31-40-years-old had the highest T. gondii seroprevalence (36.5%). Evaluation of the clinical findings of patients with concomitant toxoplasmosis and HIV infection greatly implicated fever (63.5%), headache (44.7%), rashes (41.2%) and anorexia (34.1%). This study contributes to the development of guidelines for the prevention and management of toxoplasmosis in HIV-infected patients and in apparently healthy individuals in a resource scarce setting. |
| Databáze: | OpenAIRE |
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