Extension of lymph node dissection and survival in primary gastric cancer

Autor: G B, Secco, R, Fardelli, E, Campora, S, Rovida, M, Beatini, G, Larghero, T, Testa, C, Prior
Rok vydání: 1992
Předmět:
Zdroj: International surgery. 77(4)
ISSN: 0020-8868
Popis: The histories of 429 patients who underwent surgery for primary gastric cancer at our ward from January 1970 to December 1985, were reviewed. All patients underwent surgery: potentially curative surgery, 54.8%, non-curative resection, 18.2%; palliative surgery, 27%. Nodal status was as follows: N0, 28%; N1, 17.7%; N2, 44.5%; N3, 9.8%. The incidence of N0 cases was significantly increased in Stage T1 and T2 disease compared to Stage T3 and T4 lesions (p0.001). In Stage T3 and T4 patients the incidence of distant metastases increased if lymph node involvement was also present (p0.005). In patients without nodal metastases 5-year survival was 70% (median survival: 60+ months) whereas, in patients with lymph node involvement survival was 32% (median survival: 24 months) (p0.001). Our data suggest that elective extensive lymph node dissection (R2) is indicated in all patients because survival is improved by this procedure. We recommend R3 lymph node dissection only in macroscopic N3 node involvement patients.
Databáze: OpenAIRE