| Autor: |
Olivia A, Attallah, Martin, Nady, Asmaa M, Al Gendy, Mouchira, Choucry, Mohammed N A, Khalil |
| Rok vydání: |
2022 |
| Zdroj: |
Natural product research. |
| ISSN: |
1478-6427 |
| Popis: |
A solid phase extraction (SPE) system for sesquiterpene lactones of damsissa was developed utilising molecularly imprinted polymers (MIPs). The prepared MIPs had a mesoporous structure and particle size of ≈2.65 µm with 3.99 nm pore size. Additionally, MIPs exhibited high thermal stability with degradation temperature between 209 and 459 °C. Optimized MIP-SPE protocol conditions were set at loading step: 1 mL ethanol; washing step: 1 mL water; eluting step: 4 mL methanol. Developed MIP-SPE system showed a binding capacity of 66.66 mg/g based on Langmuir isotherm which was selected as the best fitting model isotherm. Good selectivity coefficients were observed for neoambrosin of 2.37, 1.31 and 1.14 against umbelliferone, quercetin glucoside and p-coumaric acid, respectively. Furthermore, the proposed MIP-SPE protocol displayed some potential in the isolation of sesquiterpene lactones from damsissa plant extract and laid a foundation for the development of more selective MIPs to nonpolar natural products. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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