A multidisciplinary approach to giant cell tumors of tendon sheath and synovium--a critical appraisal of literature and treatment proposal
| Autor: | Lizz, van der Heijden, C L Max H, Gibbons, A Bass, Hassan, Judith R, Kroep, Hans, Gelderblom, Carla S P, van Rijswijk, Remi A, Nout, Kevin M, Bradley, Nick A, Athanasou, P D Sander, Dijkstra, Pancras C W, Hogendoorn, Michiel A J, van de Sande |
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| Rok vydání: | 2012 |
| Předmět: |
Adult
Male Indoles Antineoplastic Agents Piperazines Arthroplasty Tendons Arthroscopy Synovectomy Sunitinib Humans Pyrroles Molecular Targeted Therapy Protein Kinase Inhibitors Radioisotopes Giant Cell Tumors Synovial Membrane Tenosynovitis Middle Aged Protein-Tyrosine Kinases Magnetic Resonance Imaging Pyrimidines Chemotherapy Adjuvant Benzamides Imatinib Mesylate Female Interdisciplinary Communication Radiotherapy Adjuvant Neoplasm Recurrence Local |
| Zdroj: | Journal of surgical oncology. 107(4) |
| ISSN: | 1096-9098 |
| Popis: | Giant cell tumors deriving from synovium are classified into a localized (GCT of tendon sheath; GCT-TS) and diffuse form (diffuse-type GCT, Dt-GCT). We propose a multidisciplinary management based upon a systematic review and authors' opinion. Open excision for GCT-TS and open synovectomy (plus excision) for Dt-GCT is advised to reduce the relatively high recurrence risk. External beam radiotherapy should be considered in severe cases, as Dt-GCT commonly extends extra-articular. |
| Databáze: | OpenAIRE |
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