| Autor: |
Karla R, de Oliveira, Liane N, Rotta, Sandra C, Valle, Diogo A, Pilger, Cristina W, Nogueira, Ana M, Feoli, Elena A, Bernard, Diogo O, Souza, Marcos L S, Perry |
| Rok vydání: |
2002 |
| Předmět: |
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| Zdroj: |
Neurochemical research. 27(6) |
| ISSN: |
0364-3190 |
| Popis: |
We studied the effect of various energetic nutrients on metabolism of L-[U-14C]leucine and [1-14C]glycine in cerebral cortex of rats at different ages. At gestational age, glucose and lactate stimulated protein synthesis from L-[U-14C]leucine and [1-14C]glycine and from L-[U-14C]leucine, respectively; glucose, beta-OH-butyrate and lactate stimulated lipid synthesis from L-[U-14C]leucine. At 10 days of age, glucose, mannose, and fructose stimulated protein synthesis, and glucose and mannose stimulated oxidation to CO2 as well as lipid synthesis from L-[U-14C]leucine. In adult rats, glucose, mannose, and fructose stimulated protein synthesis from L-[U-14C]leucine and [1-14C]glycine; glutamine also markedly decreased the oxidation of L-[U-14C]leucine and [1-14C]glycine in 10-day-old and adult rats. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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