Impaired T-cell mitogen responses in some patients with thalassemia intermedia

Autor:	C G, Munn, A L, Markenson, A, Kapadia, M, de Sousa
Rok vydání:	1981
Předmět:	Adult Adolescent Pokeweed Mitogens Iron T-Lymphocytes Concanavalin A Dose-Response Relationship Immunologic Humans Thalassemia Mitogens Phytohemagglutinins Child Ferric Compounds
Zdroj:	Thymus. 3(2)
ISSN:	0165-6090
Popis:	Ten thalassemia intermedia patients were tested for their mitogenic responses to phytohemagglutinin P (PHA), concanavalin A (Con A) and pokeweed mitogen (PWM). Impaired responses to PHA and Con A were observed in patients with serum-iron levels higher than 200 microgram/dl. Responses within or slightly higher than those in the normal range were observed in patients with serum-iron lower than 200 microgram/dl. By contrast, no significant changes occurred in the majority of the responses to PWM.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=pmid________::a9a86528ce9cfa0d6588c572873ef274 https://pubmed.ncbi.nlm.nih.gov/6974915 Zobrazit plný text záznamu