| Autor: |
Dilek, Oguz, Erkin, Öztaş, Ismail Hakkı, Kalkan, Oyku, Tayfur, Bahattin, Cicek, Gulden, Aydog, Mevlut, Kurt, Yavuz, Beyazit, Digdem, Etik, Isilay, Nadir, Burhan, Sahin |
| Rok vydání: |
2012 |
| Předmět: |
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| Zdroj: |
Journal of digestive diseases. 14(3) |
| ISSN: |
1751-2980 |
| Popis: |
The aim was to compare the use of endoscopic ultrasound-guided fine needle aspiration (EUS-FNA) in cytology and the biochemical analysis of cyst fluid, together with the size of the lesion in the differentiation between benign and malignant pancreatic cystic lesions.Data of patients who underwent EUS-FNA for pancreatic cystic lesions in our center from January 2006 to October 2010 were retrospectively analyzed. The diagnostic accuracy of EUS-FNA was determined.Of the 56 patients, 37 (66.1%) had evaluable cytology for diagnosis and sufficient cyst fluid was available for biochemical analysis in 58.9% (33/56) of the patients. The sensitivity, specificity, positive predictive value and negative predictive value of EUS-FNA for detecting malignancy were 63%, 100%, 100% and 85%, respectively. EUS-FNA was the most accurate diagnostic method for differentiating malignant and benign pancreatic cystic lesions (88%). Cyst fluid carcinoembryonic antigen (CEA)365 ng/mL had a sensitivity of 100% for the detection of malignant cystic lesions.Although the rate of insufficient cyst fluid aspiration is high, the combination of cytological evaluation and CEA analysis of cyst fluid obtained by EUS-FNA is accurate in differentiating malignant cystic lesions from benign ones. Safe techniques are essential to improve the yield of cyst fluid aspiration by EUS. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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