[Membrane-bound sialoglycoproteins of the rat liver as affected by the combined action of benz(a)pyrene and sulfur dioxide]

Autor: R V, Merkur'eva, L I, Bushinskaia, N I, Skvortsova, S I, Dolinskaia, I S, Shaternikova
Rok vydání: 1981
Předmět:
Zdroj: Voprosy meditsinskoi khimii. 27(6)
ISSN: 0042-8809
Popis: Simultaneous effect of benz(a)pyrene and sulphurous gas was accompanied by distinct alteration in metabolism of sialoglycoproteins in liver tissue; at the time N-acetylneuraminic acid was redistributed in liver subcellular organelles (mitochondria, lysosomes and endoplasmic reticulum) as well as cytochromes P-450 and b5 were induced in liver microsomes. The alterations observed appear to play a definite role in manifestation of the unfavourable effect in combined action of the carcinogen and chemical contaminations of environments.
Databáze: OpenAIRE