| Autor: |
S, Bardócz, S, Tatár-Kiss, P, Kertai |
| Rok vydání: |
1986 |
| Předmět: |
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| Zdroj: |
Acta biochimica et biophysica Hungarica. 21(1-2) |
| ISSN: |
0237-6261 |
| Popis: |
After removing the left upper lobe, the remaining lung of mice undergoes compensatory growth. Increased ornithine decarboxylase activity is characteristic of the process. The effect of alpha-difluoromethylornithine was studied on the ornithine decarboxylase (E.C.4.1.1.17.) activity and on the lung growth in mice after lobectomy. Although a single injection of alpha-difluoromethylornithine inhibited ornithine decarboxylase activity, the compensatory growth of lung still occurred in spite of continuous alpha-difluoromethylornithine treatment. This suggests that polyamines, indispensable for compensatory growth, may be supplied by other sources. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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