Close spatial-temporal relationship between islet-1-expressing cells and growing primary afferent axons in the dorsal spinal cord of chick embryo

Autor:	T, Shiga, R W, Oppenheim
Rok vydání:	1999
Předmět:	Homeodomain Proteins Microscopy Electron Time Factors Spinal Cord LIM-Homeodomain Proteins Animals Nerve Tissue Proteins Tissue Distribution Chick Embryo Neurons Afferent Immunohistochemistry Axons Transcription Factors
Zdroj:	The Journal of comparative neurology. 405(3)
ISSN:	0021-9967
Popis:	The relationship between the appearance of Islet-1-expressing cells and the longitudinal growth of primary afferent axons (PAAs) in the dorsal spinal cord of chick embryos was examined. Islet-1-expressing cells first appeared in the dorsal spinal cord at embryonic days (E) 3-3.5. These immunoreactive cells were aligned in a longitudinal column in close proximity to longitudinally elongating PAAs in the presumptive dorsal funiculus. By E8, when many PAAs invade the spinal gray matter, Islet-1-expressing cells had disappeared in the dorsal spinal cord. Following the dorsoventral rotation of the spinal cord in ovo before the invasion of PAAs, a close topographical relationship between Islet-1-expressing cells and PAAs was maintained. These results suggest that Islet-1-expressing cells may play a role in the longitudinal growth of PAAs in the dorsal funiculus.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=pmid________::a894edef67eb999471836dff620351b3 https://pubmed.ncbi.nlm.nih.gov/10076933 Zobrazit plný text záznamu Plný text