[Incidence of axillary recurrence after a negative sentinel lymph node result in early stages of breast cancer: a 5-year follow-up]
| Autor: | R, Ruano Pérez, M, Ramos Boyero, J R, García-Talavera Fernández, T, Ramos Grande, J M, González-Orús, F, Gómez-Caminero López, M C, García Macias, A, Martín de Arriba |
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| Rok vydání: | 2011 |
| Předmět: |
Adult
Neoplasms Hormone-Dependent Breast Neoplasms Disease-Free Survival Rosaniline Dyes Humans Radionuclide Imaging False Negative Reactions Mastectomy Progesterone Aged Neoplasm Staging Retrospective Studies Aged 80 and over Sentinel Lymph Node Biopsy Incidence Carcinoma Ductal Breast Estrogens Middle Aged Prognosis Combined Modality Therapy Survival Analysis Carcinoma Lobular Chemotherapy Adjuvant Lymphatic Metastasis Axilla Technetium Tc 99m Sulfur Colloid Lymph Node Excision Female Radiotherapy Adjuvant Follow-Up Studies |
| Zdroj: | Revista espanola de medicina nuclear e imagen molecular. 31(4) |
| ISSN: | 2253-8070 |
| Popis: | The sentinel lymph node (SLN) biopsy is currently the procedure of choice for axillary node staging in initial stages of breast cancer. The purpose of this study is to establish our false negative rate within a 5-year follow-up period in 258 patients with breast cancer staged with this procedure.A retrospective study on 258 consecutive T1-T23 cm pN0 staged breast carcinomas treated from January 1, 2001 to December 31, 2005 was performed. The combined technique of isotope plus blue dye was used for detection. The subjects underwent a minimum follow-up of 5 years, mean 81 months, with an end of follow-up at December 31, 2010. Evidence of axillary recurrence, tumor recurrence in the breast and signs of disease progression or death were the events collected and analyzed.Of the 258 patients, 3 false negatives (1.1%) with axillary recurrence were detected at 10, 11 and 29 months of the surgery. This did not have a significant repercussion in the survival analysis on the contrary to the existence of breast recurrence or the appearance of distant metastasis in 4.7% and 6.2% patients, respectively. Global survival related with the cancer was 93.0 (240/258) and disease free survival was 89.1% (230/258).The risk of developing axillary recurrence after a negative SLN without axillary node dissection is low enough to consider the SLN procedure to be the best approach for axilla staging in early breast cancer. This staging technique also makes it possible to achieve local disease control without diminishing the survival of the patients. |
| Databáze: | OpenAIRE |
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