[Immunotherapy in complex treatment of surgical sepsis]
| Autor: | E A, Reshetnikov, G A, Baranov, M V, Chuvanov, O I, Skalozub |
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| Rok vydání: | 2008 |
| Předmět: |
Adult
Aged 80 and over Male Time Factors Adolescent Immunoglobulins Complement C3 Middle Aged Gram-Positive Bacteria Postoperative Complications Treatment Outcome Sepsis Gram-Negative Bacteria Humans Female Immunotherapy Lymphocyte Count Gram-Negative Bacterial Infections Gram-Positive Bacterial Infections Aged |
| Zdroj: | Khirurgiia. (7) |
| ISSN: | 0023-1207 |
| Popis: | The results of treatment of 73 patients with confirmed diagnosis of sepsis are analyzed. The most frequent immune disorders in septic patients are: decrease in lymphocyte count, both T (60%) and B (45.7%) populations, decrease of T-helpers and T-suppressors (52.6%) count, increase of C3-complement activator titre (50%) and phagocytic coefficient (52.4%). The more expressed immune depression observed in patients with gram-negative sepsis in comparison with the gram-positive. Standard immunoglobulins were used in the treatment of 38 patients: "Endobulin" (ImmunoAG, Austria)--in 9 cases; "Intraglobin" (Biotest, Germany)--in 14 and "Pentaglobin" (Biotest, Germany)--in 15 cases. Analyze of the control immunogramms showed the reliable improvement of immune indices and normalization of T-cell counts. Lethality among septic patients treated with immunoglobulins was 14.5%. |
| Databáze: | OpenAIRE |
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