| Autor: |
C H, Hendricks, J R, Dingfelder, W S, Gruber |
| Rok vydání: |
1976 |
| Předmět: |
|
| Zdroj: |
Prostaglandins. |
| ISSN: |
0090-6980 |
| Popis: |
A salastic vaginal device containing either 0.5% or 1.0% concentrations of 15(s)-15 methyl prostaglandin F2 alpha methyl ester was used to induce therapeutic abortion in 22 patients at 6-16 weeks gestation. The 1.0% device appeared to be an effacious and safe method with cumulative abortion rates similar to that seen with intra-amniotic and intramuscular prostaglandin administration. The 0.5% device appears less effective. Bothersome side effects of emesis and diarrhea were seen with both devices although no serious complications occurred. Uterine activity and serum levels of 15(s)-15 methyl PGF2alpha appeared to reflect the concentration of prostaglandin in the device. The use of a prostaglandin-containing silastic vaginal device appears to be a safe method of pregnancy termination which is convenient, effective, and applicable to a broad range of gestational ages. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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