Cul3 is required for normal development of the mammary gland

Autor: Cristina M, Cummings, Jeffrey D, Singer
Rok vydání: 2020
Předmět:
Zdroj: Cell and tissue research. 385(1)
ISSN: 1432-0878
Popis: Cullin 3 (Cul3) has recently been implicated in a multitude of different processes, including the oxidative stress response, autophagy, tumorigenesis, and differentiation. To investigate the role of Cul3 in mammary gland development, we created a mouse model system using Cre-lox targeting where Cul3 is specifically deleted from the mammary gland. Such MMTV-Cre Cul3
Databáze: OpenAIRE