Cul3 is required for normal development of the mammary gland
Autor: | Cristina M, Cummings, Jeffrey D, Singer |
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Rok vydání: | 2020 |
Předmět: | |
Zdroj: | Cell and tissue research. 385(1) |
ISSN: | 1432-0878 |
Popis: | Cullin 3 (Cul3) has recently been implicated in a multitude of different processes, including the oxidative stress response, autophagy, tumorigenesis, and differentiation. To investigate the role of Cul3 in mammary gland development, we created a mouse model system using Cre-lox targeting where Cul3 is specifically deleted from the mammary gland. Such MMTV-Cre Cul3 |
Databáze: | OpenAIRE |
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