| Autor: |
V I, Rykova, S A, Kropotova, V I, Kaledin, L A, Semenova |
| Rok vydání: |
1990 |
| Předmět: |
|
| Zdroj: |
Biokhimiia (Moscow, Russia). 55(3) |
| ISSN: |
0320-9725 |
| Popis: |
Using electrophoresis in agarose gel, a comparative study of composition of membrane-bound glycosaminoglycans (GAG) from normal mouse liver cells and from o-aminoazatoluene-induced mouse hepatoma cells was carried out. Differences in the composition and localization of GAG were revealed. The plasma membrane fraction of hepatoma cells contained no GAG; the bulk of GAG (approximately 98%) was localized in the plasma membrane free fraction. Within this fraction GAG contained no heparan sulfates with a high electrophoretic mobility that were detected in plasma membranes of normal liver cells. The possible involvement of proteoglycans bound to cell surface in transmembrane signal transfer is discussed. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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