Lipidomic and Metallomic Alteration of

Autor: Bastian, Blume, Vera, Schwantes, Michael, Witting, Heiko, Hayen, Philippe, Schmitt-Kopplin, Patrick O, Helmer, Bernhard, Michalke
Rok vydání: 2023
Zdroj: Journal of proteome research.
ISSN: 1535-3907
Popis: Parkinson's disease (PD) progresses with the loss of dopaminergic neurons in the substantia nigra pars compacta region of the brain. The superior mechanisms and the cause of this specific localized neurodegeneration is currently unknown. However, experimental evidence indicates a link between PD progression and reactive oxygen species with imbalanced metal homeostasis. Wild-type
Databáze: OpenAIRE