Risk factors associated with the development of hyperamylasemia and post-ERCP pancreatitis in the Cuban National Institute

Autor: Héctor Ruben, Hernández Garcés, Alonso, Almeida Linnet, María del Rosario, Abreu Vázquez, Luis, Calzadilla Bertot, Kevin, Peña, Yudit, Andrain Sierra, Issoufo, Moutary, Nilmer, Segura Fernández
Rok vydání: 2014
Předmět:
Zdroj: Revista de gastroenterologia del Peru : organo oficial de la Sociedad de Gastroenterologia del Peru. 34(2)
ISSN: 1609-722X
Popis: Acute pancreatitis is the most common complication in ERCP, and some risk factors were associated with the development of hyperamylasemia and post-ERCP pancreatitis.identifying new factors associated with the development of hyperamylasemia or post-ERCP pancreatitis in patients attended at our center.A (retrospective) cohort study was carried out in 170 patients on which a diagnostic-therapeutic ERCP was done due to biliopancreatic disease. 67 patients developed hyperamylasemia (39.4%) and 6 post-ERCP pancreatitis (3.5%). The following diagnostic criteria were applied: Hyperamylasemia: increase in the serum amylase level above the normal value (90 I/U). Acute post-ERCP pancreatitis: clinical: continuous abdominal pain for over 24 hours and biochemical: elevation of amylase3 times above normal value (90 U/I).The number of cannulations more than 4 (19 patients), (p=0.006; RR= 3.00) was associated significantly with the development of hyperamylasemia and the placing of biliary stent (14 patients), (p=0.00; RR= 0.39) was a protective factor. The factors associated with the development of post-ERCP pancreatitis were related with the patient (peridiverticular location of the papilla (p=0.00; RR= 2.00) and the sphincter of Oddi dysfunction (p=0.000; RR=1.20).Technical factors were associated with the development of hyperamylasemia, however, the factors associated with the development of post-ERCP pancreatitis in our universe of study were related mainly with the patient.
Databáze: OpenAIRE