| Autor: |
Ichiro, Amano, Naoki, Sawai, Chiemi, Mizuno, Yukie, Shaura, Masatake, Nishiwaki, Ryuji, Horimoto, Hirohisa, Oya, Ryusuke, Kato, Kojiro, Seki, Hiroaki, Hashimoto, Yoshiro, Amakata, Junko, Matsumoto, Izumi, Tanaka, Masayuki, Mizuno, Toshihide, Shima, Takeshi, Okanoue |
| Rok vydání: |
2012 |
| Předmět: |
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| Zdroj: |
Gan to kagaku ryoho. Cancerchemotherapy. 39(13) |
| ISSN: |
0385-0684 |
| Popis: |
A 74-year-old man was referred to our hospital because of abdominal distension. Upper gastrointestinal endoscopy revealed advanced gastric cancer and early gastric cancer. HER2-positive and AFP-producing gastric cancer with peritonitis carcinomatosa showing no indication for operation was diagnosed by histopathological and radiological examinations. He was treated with trastuzumab, docetaxel, and S-1 combination chemotherapy. At the end of the second course of therapy, the primary lesion was remarkably decreased in size and was associated with a significant decrease in serum AFP level. No serious adverse events occurred except for grade 3-4 leukopenia and neutropenia. We carried out eight courses of chemotherapy. Trastuzumab, docetaxel, and S-1 combination chemotherapy promise to be one of the effective treatments for HER2-positive and AFP-producing gastric cancer that have no indication for radical cure excision. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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