The effects of starches on mechanical properties of paracetamol tablet formulations. I. Pregelatinization of starch binders

Autor:	Gbenga, Alebiowu, Oludele Adelanwa, Itiola
Rok vydání:	2004
Předmět:	Chemistry Pharmaceutical Tensile Strength Starch Mechanics Zea mays Sorghum Acetaminophen Tablets
Zdroj:	Acta pharmaceutica (Zagreb, Croatia). 53(3)
ISSN:	1330-0075
Popis:	A study has been made of the effects of pregelatinization of native sorghum and plantain starches on the mechanical properties of a paracetamol tablet formulation in comparison with corn starch BP. The mechanical properties tested, viz. tensile strength (T) and brittle fracture index (BFI) of the paracetamol tablets were affected by pregelatinization of the starch. The results suggest that pregelatinized starches may be useful as binders when a particular degree of bond strength and brittleness is desired.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=pmid________::a613db08db8bae0361796aaa9f394b30 https://pubmed.ncbi.nlm.nih.gov/14769246 Zobrazit plný text záznamu