Cardiovascular disease risk factors in Pakistani population with newly diagnosed Type 2 diabetes mellitus: A cross-sectional study of selected family practitioner clinics in four provinces of Pakistan (CardiP Study)
| Autor: | Syed Abbas, Raza, Mariam, Hassan, Farhana, Badar, Farah, Rasheed, Fouzia, Meerza, Sumeyya, Azam, Ali, Jawa, Imtiaz, Hassan, Faisal Masood, Qureshi, Zakir, Alvi, Saeed Ahmed, Mahar, Azizul Hasan, Aamir, Rauf, Niazi, Najmul, Islam |
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| Rok vydání: | 2019 |
| Předmět: |
Adult
Blood Glucose Glycated Hemoglobin Male Cholesterol HDL Age Factors Blood Pressure Coronary Disease Cholesterol LDL Lipoproteins VLDL Middle Aged Stroke Cholesterol Cross-Sectional Studies Diabetes Mellitus Type 2 Cardiovascular Diseases Risk Factors Humans Female Pakistan Prospective Studies Family Practice Triglycerides |
| Zdroj: | JPMA. The Journal of the Pakistan Medical Association. 69(3) |
| ISSN: | 0030-9982 |
| Popis: | To explore cardiovascular risk factors in people with newly-diagnosed type 2 diabetes mellitus.The cross-sectional, prospective, multicentre, study was conducted from June 2014 till July 2015 at family practice clinics in 27 cities across Pakistan, and comprised individuals aged 30-50 years diagnosed with type 2 diabetes mellitus within the preceding six months. Laboratory investigations were conducted at Shaukat Khanum Memorial Cancer Hospital and Research Centre, Lahore, and Aga Khan University Hospital, Karachi. The 10-year absolute risk of fatal or non-fatal coronary heart disease and stroke was calculated using the United Kingdom Prospective Diabetes Study Risk Engine version 2.0. Data were analysed using SPSS 19.Out of 888 subjects, 362(40.8%) were women and 526(59.2%) were men. The overall mean presenting age was 42.4}5.8 years. After stratification by age, those ≥40 years were significantly associated with higher glycated haemoglobin (p=0.02) and those ≤39 years were associated with higher levels of very low density lipoprotein (p=0.001) and triglyceride (p=0.006). The mean risk estimate for CHD was 9.7% (95% Confidence Interval (CI) 9.0- 10.1)), for fatal CHD 4.4% (95% CI 4.0-4.6), for stroke 1.5% (95% CI 1.2-1.7), and for fatal stroke 0.25% (95% CI 0.24- 0.26).There is a need for screening cardiovascular risk factors even in younger age groups of newlydiagnosed diabetes. |
| Databáze: | OpenAIRE |
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