Cardiovascular Function in Obstructive Sleep Apnea Patients with Controlled Hypertension

Autor: Magdalena, Kostrzewska, Marcin, Grabicki, Tomasz, Piorunek, Tomasz, Krauze, Damian, Skrypnik, Halina, Batura-Gabryel, Tomasz, Trafas, Paweł, Bogdański, Andrzej, Wykrętowicz, Przemysław, Guzik
Rok vydání: 2020
Předmět:
Zdroj: Advances in experimental medicine and biology. 1271
ISSN: 0065-2598
Popis: This study investigated hemodynamic characteristics of obstructive sleep apnea (OSA) accompanied by hypertensive disease in obese men, in whom blood pressure was pharmacologically controlled within the normal range, not exceeding 140/90 mmHg. There were 21 severe OSA patients (mean age 54.1 ± 9.3 years, apnea-hypopnea index of 47.1 ± 18.8 episodes per hour) included in the study, in whom OSA was diagnosed with polysomnography. The control group consisted of healthy normotensive age-matched subjects. Hemodynamic profile was recorded nonivasively with impedance cardiography. Brachial blood pressure and radial artery tonometry were performed to capture and reconstruct peripheral radial and central aortic pressure waveforms in both groups of subjects. Compared to healthy men, OSA patients had a significantly higher body mass index (BMI); the mean increase in BMI amounted to 6.4 ± 1.2 kg/m
Databáze: OpenAIRE