Rhabdomyolysis associated with influenza A/H1N1 2009 infection in a pediatric patient

Autor: Naruhiko, Ishiwada, Nobuyuki, Takada, Tomoko, Okunushi, Haruka, Hishiki, Harutaka, Katano, Noriko, Nakajima, Yoichi, Kohno
Rok vydání: 2012
Předmět:
Zdroj: Pediatrics international : official journal of the Japan Pediatric Society. 54(5)
ISSN: 1442-200X
Popis: The influenza A/H1N1 2009 epidemic has spread to many countries since 2009, including Japan. We report an immune-competent child involving rhabdomyolysis and compartment syndrome associated with influenza A/H1N1 2009. The patient was demonstrated rhabdomyolysis with myoglobinuria, hyperkalemia, cardiac dysfunction and compartment syndrome that arose during convalescence from influenza A/H1N1 2009 infection. Although RT-PCR of muscle tissue yielded negative results for influenza A/H1N1 2009 RNA and no viral positive-antigen cells were detected in the muscle lesions, the clinical picture suggested rhabdomyolysis associated with influenza A/H1N1. Rhabdomyolysis should be considered in the evaluation of muscle symptoms such as myalgia associated with novel influenza A/H1N1 2009 virus infection, particularly in critically ill patients.
Databáze: OpenAIRE